A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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Nanotechnology delivers A selection of prospects to add to biology. Right here I will current illustrations the place nanofabrication – a chance to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
Our group scientific studies bacterial cell division and is particularly aiming to represent a ‘bottom up biology’ in synthetic cells which can autonomously divide. Our key fascination lies in cell division, chromatin composition, and spatial Regulate.
As being a human being, I provide the biblical assignment to explore and use anything in creation for the benefit of my neighbour. I usually do not practical experience any conflict between faith and science. On the contrary, my faith stimulates me to perform science, being open up-minded in the world.’
Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters
2015, discovery that condensin is a really adaptable protein construction; and initial detection of DNA knots using nanopores
Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the movement with the DNA rod is displayed.
‘At first we looked at biological devices with a physical look at and acted on The premise from the equipment we realized. It took a number of years prior to we started out Performing more on the big biological troubles. I then began to connect with it nanobiology, a term that did not exist at time.
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim of the pore is highlighted in pink, plus a 3D rendering of the movement of the DNA rod is shown.
In 1993, being a youthful and keen associate professor at Delft College of Technology, I had originally concentrated the research attempts of my group on measuring the electrical conductance of one conducting-polymer molecule. Within two a long time, we had made a tool in which just one wire of the phthalocyaninepolysiloxane polymer was linked concerning two intently spaced metal nanoelectrodes.
Resolving the phase dimension in condensin-driven DNA loop extrusion identifies ATP binding as being the phase-producing process
Case in point (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in grey, the rim of your pore is highlighted in crimson, and a 3D rendering with the motion with the DNA rod is displayed.
Later on we spoke once more briefly due to the fact Dekker felt that our dialogue of his faith speedily grew to become purely philosophical, While Furthermore, it concretely will help him in his get the job done.
Visualization of unstained DNA nanostructures with Highly developed in-focus transmission electron microscopy techniques
The biophysicist from Delft – who continues to be one of the most cited researchers from the Netherlands For several years – normally takes his duty to contribute into the rationalization and popularisation of his operate on the border of physics and biology very seriously and consistently seems inside the media; if not to look at his operate, then about the relationship ceesdekker concerning science and his Christian religion.